Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. (ISAS)
The Leibniz-Institut für Analytische Wissenschaften – ISAS –develops analytical technologies and combines them into new high-performance measuring strategies for health research. The goal is to develop analytical methods for precision medicine tailored to individual patients in order to optimise the prevention, diagnostics and (personalized) therapy of cardiovascular diseases, autoimmune diseases and cancer, for example. The institute's applied basic research focuses on translation into the clinic. That is why ISAS researchers cooperate at an early stage with partners from various university hospitals and the healthcare industry.
In order to understand when and where in the body the biological decision between health and disease is made, analytical methods that simultaneously map information on different classes of molecules and their spatial distribution are needed. The core of ISAS' research concept therefore lies in 4D analytics. In short, 4D analytics comprises a quantitative and qualitative analysis of biological systems as well as time- and spatially-resolved identification of (bio-)molecules.
Scientists at ISAS develop combined methods in which complementary, coordinated analytical technologies like mass spectrometry and microscopy are used as integrative measuring strategies. The information obtained with the help of 4D analytics is important for a deep understanding of the causes of diseases at the molecular level. They are also the basis for the development of new screening or therapeutic strategies, for example.
