Stellenangebot vom 10.01.2019
The Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Jena (Germany), is a federal and state government-funded research institute and member of the Leibniz Association (Leibniz-Gemeinschaft).
FLI’s internationally visible and highly competitive research is focused on understanding the mechanisms of aging and associated age-related diseases. More than 220 scientists from over 30 countries are currently investigating the molecular mechanisms of aging and the occurrence of age-related diseases. Our aim is to create the basis for new approaches in medicine as a way to improve health in the elderly.
The ʺMembrane Trafficking in Agingʺ group, headed by Dr. Christoph Kaether invites applications for a
Postdoc Position (m/f)
Tasks and Challenges:
The group works on the structure and function of the endo-plasmic reticulum (ER). We are interested in the molecular mechanisms of ER export, specifically in a step that is sensitive to the secretion inhibitor FLI-06 that we identified (Krämer et al. Nature Chem Biol 2013, Yonemura et al. JCS 2016).
Using CRISPR-based gain- and loss-of-function screens we identified a number of genes that are involved in this step.
The applicant’s task is to further characterize the hits using cell biological and biochemical tools (construction of fusion proteins, confocal-, live- and super resolution-microscopy, Western Blot, Co-immunoprecipitation, siRNA, shRNA, CRISPR).
Candidates are encouraged to send their application referring to Job-ID 1901 until February 17, 2019, jobs(at)leibniz-fli.de as single-pdf-document including full CV, publication list or
Leibniz Institute on Aging — Fritz Lipmann Institute (FLI)