Sonopharmocology – Activation of Drugs by Ultrasound (ACTISONO) – Leibniz ScienceCampus Aachen

Treating patients with medicines is one of the most important and frequently used medical therapies available to us. However, their use is often a compromise between desired treatment and undesirable side effects. The associated disadvantages often have to be accepted due to the limited possibilities of only delivering the active ingredients to the necessary location in the body.

It is therefore all the more important that drug treatments are designed to be as precise and controllable as possible in order to administer the active ingredients at the site of action in the body. This requires new technologies, such as the control of bioactive substances "from a distance".

This is precisely where the Leibniz ScienceCampus "ACTISONO" comes in. The aim is to use ultrasound to control the activity of drugs and therapeutically active nucleic acids. An interdisciplinary team of researchers from the fields of polymer chemistry, medicine, biology and engineering are working together on various scientific and methodological projects. Among other things, they are developing so-called microbubbles for the activation of antibiotics by ultrasound or researching how the regeneration of the liver after an operation can be improved by ultrasound.

Their aim is to revolutionize the activation of active substances deep within the body and to establish the research field of "sonopharmacology".